*,*:before,*:after{box-sizing:border-box;margin:0;padding:0}:root{--bg-base: #0d1117;--bg-surface: #161b27;--bg-elevated: #1c2333;--bg-input: #1a2035;--border: #2a3347;--border-focus: #3b82f6;--text-primary: #e2e8f0;--text-secondary: #8892a4;--text-muted: #4a5568;--blue: #3b82f6;--blue-light: #93c5fd;--blue-dim: #1e3a5f;--green: #10b981;--green-dim: #064e3b;--amber: #f59e0b;--amber-dim: #451a03;--red: #ef4444;--red-dim: #450a0a;--radius-sm: 6px;--radius-md: 10px;--radius-lg: 14px;--font: "DM Sans", system-ui, sans-serif;--font-mono: "DM Mono", monospace}html,body,#root{height:100%;background:var(--bg-base);color:var(--text-primary);font-family:var(--font);font-size:15px;line-height:1.6;-webkit-font-smoothing:antialiased}.app{min-height:100vh;display:flex;flex-direction:column}.med1-topbar{display:flex;align-items:center;gap:0;background:#060911;border-bottom:1px solid var(--border);padding:0 1rem;height:36px;position:sticky;top:0;z-index:200}.med1-topbar a{display:flex;align-items:center;gap:.4rem;padding:.4rem .75rem;color:var(--text-muted);text-decoration:none;font-size:.75rem;font-weight:500;border-radius:var(--radius-sm);transition:color .15s,background .15s;white-space:nowrap}.med1-topbar a:hover{color:var(--text-primary);background:var(--bg-elevated)}.med1-topbar a.active{color:var(--blue)}.header{display:flex;align-items:center;gap:14px;padding:1rem 2rem;border-bottom:.5px solid var(--border);background:var(--bg-surface);position:sticky;top:36px;z-index:100}.header-logo{height:38px;width:auto;object-fit:contain}.header-divider{width:.5px;height:28px;background:var(--border)}.header-title{font-size:15px;font-weight:500;color:var(--text-secondary);letter-spacing:.01em}.header-user{margin-left:auto;display:flex;align-items:center;gap:10px}.user-name{font-size:13px;color:var(--text-muted)}.btn-logout{font-size:13px;padding:5px 12px;background:transparent;border:.5px solid var(--border);border-radius:var(--radius-sm);color:var(--text-secondary);cursor:pointer;font-family:var(--font);transition:border-color .15s,color .15s}.btn-logout:hover{border-color:var(--text-muted);color:var(--text-primary)}.main{flex:1;max-width:820px;width:100%;margin:0 auto;padding:2.5rem 1.5rem}.search-label{font-size:11px;text-transform:uppercase;letter-spacing:.08em;color:var(--text-muted);margin-bottom:8px}.search-wrap{position:relative;margin-bottom:1.25rem}.search-icon{position:absolute;left:14px;top:50%;transform:translateY(-50%);color:var(--text-muted);pointer-events:none}.search-input{width:100%;padding:13px 16px 13px 44px;background:var(--bg-input);border:.5px solid var(--border);border-radius:var(--radius-md);color:var(--text-primary);font-size:15px;font-family:var(--font);outline:none;transition:border-color .15s}.search-input:focus{border-color:var(--border-focus)}.search-input::placeholder{color:var(--text-muted)}.autocomplete-list{position:absolute;top:calc(100% + 4px);left:0;right:0;background:var(--bg-elevated);border:.5px solid var(--border-focus);border-radius:var(--radius-md);z-index:50;overflow:hidden;box-shadow:0 8px 24px #0006}.autocomplete-item{padding:10px 16px;cursor:pointer;transition:background .1s}.autocomplete-item:hover{background:var(--blue-dim)}.autocomplete-item-name{font-size:14px;color:var(--text-primary)}.autocomplete-item-sub{font-size:12px;color:var(--text-muted);margin-top:1px}.selected-pill{display:inline-flex;align-items:center;gap:8px;background:var(--blue-dim);border:.5px solid var(--blue);border-radius:20px;padding:5px 10px 5px 14px;font-size:13px;color:var(--blue-light);margin-bottom:1.25rem}.pill-clear{cursor:pointer;color:var(--text-muted);font-size:18px;line-height:1;padding:0 2px;transition:color .1s}.pill-clear:hover{color:var(--text-primary)}.filters{display:grid;grid-template-columns:1fr 1fr;gap:12px;margin-bottom:2rem}.filter-group label{display:block;font-size:11px;text-transform:uppercase;letter-spacing:.08em;color:var(--text-muted);margin-bottom:7px}.filter-group select{width:100%;padding:10px 36px 10px 14px;background:var(--bg-input);border:.5px solid var(--border);border-radius:var(--radius-md);color:var(--text-primary);font-size:14px;font-family:var(--font);outline:none;cursor:pointer;transition:border-color .15s;-webkit-appearance:none;-moz-appearance:none;appearance:none;background-image:url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' width='12' height='12' viewBox='0 0 24 24' fill='none' stroke='%234a5568' stroke-width='2'%3E%3Cpath d='m6 9 6 6 6-6'/%3E%3C/svg%3E");background-repeat:no-repeat;background-position:right 12px center}.filter-group select:focus{border-color:var(--border-focus)}.result-card{background:var(--bg-surface);border:.5px solid var(--border-focus);border-radius:var(--radius-lg);padding:1.75rem;animation:fadeIn .2s ease}@keyframes fadeIn{0%{opacity:0;transform:translateY(6px)}to{opacity:1;transform:translateY(0)}}.card-top{display:flex;align-items:flex-start;justify-content:space-between;margin-bottom:1.25rem;padding-bottom:1.25rem;border-bottom:.5px solid var(--border)}.card-name{font-size:22px;font-weight:500;color:var(--text-primary)}.card-klasse{font-size:13px;color:var(--text-muted);margin-top:3px}.card-indikation{font-size:12px;color:var(--blue-light);margin-top:6px}.badge{font-size:11px;font-weight:500;padding:4px 10px;border-radius:20px;white-space:nowrap}.badge-oral{background:var(--green-dim);color:#6ee7b7}.badge-iv{background:var(--blue-dim);color:var(--blue-light)}.badge-im{background:#2d1b69;color:#c4b5fd}.dosing-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:10px;margin-bottom:1.25rem}.dosing-box{background:var(--bg-base);border-radius:var(--radius-sm);padding:10px 14px}.dosing-box-label{font-size:10px;text-transform:uppercase;letter-spacing:.08em;color:var(--text-muted);margin-bottom:4px}.dosing-box-value{font-size:15px;font-weight:500;color:var(--text-primary);font-family:var(--font-mono)}.info-section{margin-top:1rem}.info-block{margin-bottom:10px}.info-block-label{font-size:10px;text-transform:uppercase;letter-spacing:.08em;color:var(--text-muted);margin-bottom:5px}.info-block-text{background:var(--bg-base);border-radius:var(--radius-sm);padding:10px 14px;font-size:14px;color:var(--text-secondary);line-height:1.65}.info-block-text.warning{border-left:3px solid var(--amber);color:#fbbf24;background:var(--amber-dim)}.info-block-text.danger{border-left:3px solid var(--red);color:#fca5a5;background:var(--red-dim)}.state-hint{text-align:center;padding:3rem 1rem;color:var(--text-muted);font-size:14px}.no-result{text-align:center;padding:2.5rem 1rem;background:var(--bg-surface);border:.5px solid var(--border);border-radius:var(--radius-lg);color:var(--text-muted);font-size:14px}.loading{display:flex;align-items:center;gap:10px;color:var(--text-muted);font-size:14px;padding:1rem 0}.spinner{width:16px;height:16px;border:2px solid var(--border);border-top-color:var(--blue);border-radius:50%;animation:spin .7s linear infinite}@keyframes spin{to{transform:rotate(360deg)}}.login-screen{min-height:100vh;display:flex;align-items:center;justify-content:center;background:var(--bg-base);padding:2rem}.login-card{background:var(--bg-surface);border:.5px solid var(--border);border-radius:var(--radius-lg);padding:2.5rem 2rem;width:100%;max-width:380px;text-align:center}.login-logo-wrap{margin-bottom:1.75rem}.login-logo{height:44px;width:auto;object-fit:contain}.login-title{font-size:18px;font-weight:500;color:var(--text-primary);margin-bottom:.5rem}.login-sub{font-size:14px;color:var(--text-muted);margin-bottom:2rem;line-height:1.6}.btn-login{width:100%;padding:13px;background:var(--blue);border:none;border-radius:var(--radius-md);color:#fff;font-size:15px;font-weight:500;font-family:var(--font);cursor:pointer;transition:background .15s}.btn-login:hover{background:#2563eb}.error-msg{margin-top:1rem;font-size:13px;color:#fca5a5}@media (max-width: 600px){.header{padding:.75rem 1rem}.main{padding:1.5rem 1rem}.filters{grid-template-columns:1fr}.dosing-grid{grid-template-columns:1fr 1fr}}